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Antidepressants and Bleeding Risk: What’s the Link?

Results showed an increased risk of bleeding with SRIs by 1.16-2.36 times with an even higher 3.17- to 10.9-fold. risk with concomitant NSAIDs.

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Depression Associated With More Severe Disease Activity, Functional Impairment in axSpA

Depression is common in patients with axSpA and is associated with more severe disease activity and functional impairment.

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Marijuana Use Associated With Poorer Depression Outcomes, Increased Suicidal Ideation

These data suggest that marijuana use, particularly non-medical use, is associated with poorer depression and anxiety outcomes in psychiatric patients.

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Brain Region Connectivities Mediate the Association Between Depression and Sleep Quality

These data suggest a neurologic basis for the relationship between sleep quality and depressive symptoms, even among patients with no clinical diagnosis of depression.

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The Many Misconceptions of Catatonia: Treatment Is Often Successful With the Right Knowledge

One of the main reasons for the frequent misdiagnosis of catatonia is the continuing misconception that it is synonymous with schizophrenia.

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Bipolar Disorder Knowledge Scale Shows Internal Consistency and Reliability

A 25-item true and false questionnaire was used to assess knowledge of bipolar disorder.

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App-Supported Inpatient Intervention to Prevent Postdischarge Suicide Attempts

The rate of suicide attempts in participants assigned to intervention plus treatment as usual was half of that in participants in the treatment as usual-alone group.

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Orbitofrontal Connectivity Associated With Mood, Anxiety Symptoms in Adolescents Who Use Marijuana

Marijuana usage is increasing in adolescents, and the rate of comorbidity with mood and anxiety disorders is high. These findings may aid in identifying adolescents who are potentially at risk.

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Escitalopram Treatment After Acute Coronary Syndrome May Improve Long-term Outcomes

Depression is associated with poorer outcomes in ACS and these findings suggest that this course of treatment may improve long-term major adverse cardiac event outcomes.

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Predispositions to Violence Influenced by Early Life Conduct Disturbances in Schizophrenia

Investigators examined traits which may predispose to violence in patients with schizophrenia, including psychopathic and impulsive traits along with aggression traits.

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Sudden Parental Death Significantly Increases Incident Depression in Offspring

Incidence of depression occurred mostly within the first 2 years after parental death in patients whose parent died at the age of 12 or younger.

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Second Generation Long-Acting Injectable Drugs Effective for Schizophrenia

The findings support second generation long-acting injectable antipsychotic drug use as early treatment option to increase treatment adherence and to decrease the risk of relapse, hospitalization, and deteriorating social functions.

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Certain Neuroinflammatory Biomarkers Associated With Depressive Symptoms

These data substantiate claims that certain neuroinflammatory biomarkers may predict depression symptoms or severity and could be useful in developing diagnostic and treatment strategies.

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OCD Associated With Socioeconomic Factors and Mental Health Comorbidities

A lower socioeconomic status, childhood maltreatment, and the presence of comorbid mental health conditions were associated with diagnosed OCD in the studied Canadian population.

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Sex-Related Cognitive Variations Disrupted in Bipolar Disorder

The potential effects of sex specific diagnosis on neurocognitive function was examined in patients with bipolar disorder.

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Body Dysmorphic Disorder: Ethical Questions and Surgical Contraindications

The potential consequences of providing cosmetic treatment to a patient with BDD can extend beyond ethical concerns.

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FAST Scores for Functioning Are Meaningful for Recovery in Bipolar Disorder

There is no distinct cut off for the Functional Assessment Short Test between none, mind, moderate, and severe functional impairment.

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