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Mortality Gap Widens in Bipolar Disorder vs General Population

Investigators examined whether the mortality gap has increased over the last 20 years in patients with bipolar disorder.

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Predictors of Suicide Attempt and the Effect of Treatment-Seeking Behavior

Clinicians assessing individuals with major depressive episodes are urged to inquire about prior suicide attempts, recurrent thoughts of death, quality of life, and the severity of depressive symptomatology.

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Psychotic-Like Experiences in Adolescence Could Cause Neural Changes During Reward Processing

These findings indicate that developmental changes are part of the etiology of psychotic disorders, and compensatory cognitive control could be a mechanism to contextualize the psychotic-like experiences precluding psychosis during adolescence.

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Polypharmacy Therapy for Schizophrenia Increases Risk for Type 2 Diabetes

Investigators aimed to assess the effect of psychotropic medications, BMI, duration of schizophrenia, number of hospitalizations, and physical activity on the risk for T2D.

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Study Finds Clinical Trials for Newer, Breakthrough Therapies Lacking

More than half of the new approvals of Breakthrough Therapy drugs were based on a single pivotal trial.

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Screening for Bipolar Disorder in Women With Postpartum Depression

Several studies have reported a high prevalence of hypomanic and manic symptoms in women with postpartum depression.

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Peer-Supported Self-Management in Mental Healthcare Patients Reduces Readmission to Acute Care

Time to readmission was significantly longer in the intervention group than in the control group.

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Predictors of Suicide Risk in Bipolar Disorder Vary by Sex

Patients with bipolar disorder face a risk for suicide that is up to 20 times greater than that of the general population. However, the specific factors that contribute to this risk are not necessarily comparable across all populations.

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Psilocybin Study Gets Green Light From FDA for Treatment-Resistant Depression

The trial will be a Phase 2b dose-ranging study (N=216) with patients from 12-15 research centers across Europe and North America.

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Symptoms of Sleep Disorders Prevalent in Psychiatric Illnesses

The authors argue that identifying and treating sleep disorders during early stages may have a positive impact on outcomes in psychiatric patients.

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Tobacco Smoking May Be an Independent Risk Factor for Schizophrenia

Maternal smoking may be a modifiable risk factor for the development of schizophrenia in offspring.

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Video-Feedback Intervention to Promote Positive Foster Parenting

The current study aims to test the effectiveness of a video-feedback intervention in increasing caregiver sensitivity to foster children.

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Cannabis Use in Bipolar Disorder Presents a Treatment Challenge

Cannabis use can complicate the management of bipolar disorder by virtue of causing mood instability and psychosis in certain patients with bipolar disorder. Other patients believe it helps manage their moods.

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Perinatal Photoperiod May Influence Lifetime Depression in Offspring

Extreme differences in daily photoperiod during pregnancy may be related to risk for lifetime depression in offspring.

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Concierge Medicine Is Changing the Physician Practice Landscape

In addition to a better work-life balance, concierge medicine can reduce the number of patients a physician needs to see in order to make a living.

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KaPow: Using Medical Comics as a Tool for Patient Education

Medical comic books may be an acceptable form of patient education material, but clinicians should assess and honor patient preferences before providing these materials.

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Reducing Off-Label Quetiapine Prescribing the Old-Fashioned Way: Snail Mail

Despite the associated risk for death and cognitive decline, “off-label” prescribing of antipsychotics in patients with dementia has increased.