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Bipolar Inventory of Symptoms Scale Displays High Sensitivity, Low Specificity for Comorbid Anxiety Disorders

Investigators examined the prevalence and impact of comorbid anxiety in patients with bipolar disorder using the Bipolar Inventory of Symptoms Scale.

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Missed General Practice Appointments Linked To Increased Morbidity, Mortality

For patients with both physical and mental health-related long-term conditions, missing healthcare appointments is associated with an increased risk of multimorbidity.

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Benzodiazepines, if Prescribed, May Not Affect Methadone Treatment Retention

The use of benzodiazepine, only if prescribed, may not affect retention of methadone medication-assisted treatment.

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Describing Cognitive Domains in Individuals With Bipolar Disorder

Investigators sought to identify cognitive subgroups in patients with bipolar disorder, no known neuropsychological performance issues, and no drug or alcohol dependence or abuse issues.

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Utilizing Family Risk Profiles to Predict Subsequent Anxiety, Depression in Children

Data underscore the prospective impact of parental drinking and psychiatric symptoms on childhood mental health outcomes.

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Brain-Derived Neurotrophic Factor: An Effective Biomarker for ECT Response in MDD?

Researchers found no association between depression severity and brain-derived neurotrophic factor (BDNF) levels, and no correlation between BDNF levels and response to electroconvulsive therapy.

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Doctoring Thoughtfully Through Trauma-Informed Care

It’s no surprise that recent events, including the confirmation hearings for Supreme Court Justice Brett Kavanaugh, have elicited a number of painful memories for people across the United States.

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Youths Who Use Marijuana Are at Increased Risk for Acute Psychotic Symptoms

Investigators examined whether adolescents who use marijuana heavily develop acute psychotic symptoms at a much higher rate than youths who use marijuana minimally or not at all.

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Food Insecurity Increases Risk for Binge Eating Disorder and Obesity

Investigators observed a link between food insecurity — difficulty affording enough food to support regular, balanced meals — and increased probability of binge-eating disorder and obesity, according to study results.

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How Should Clinicians Discuss Prognosis With Patients?

Talking to sick patients about their future health prospects is a challenge.

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Aripiprazole, Bupropion Augmentation More Cost-Effective Than Just Bupropion

Investigators evaluated the cost-effectiveness of augmentation with either aripiprazole or bupropion in patients with depression compared with switching to a new antidepressant.

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Valbenazine May Improve Movement Disorders in Patients With Mood Disorders

An analysis of once-daily valbenazine trials revealed improvements in tardive dyskinesia in patients with mood disorders.

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Risk for Depression and Suicidal Ideation Elevated Among Patients With Atopic Dermatitis

Patients with atopic dermatitis have a higher likelihood of clinical depression and suicidality.

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Ketamine May Be Equally Effective in Anxious vs Nonanxious Depression

Researchers found that there is a potential for the use of intravenous ketamine for anxious treatment-resistant depression.

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FDA: Important Updates to the Clozapine REMS Program

Products covered under the Clozapine REMS program include Clozaril (HLS Therapeutics), Fazaclo (Jazz), and Versacloz (TruPharma), in addition to all generic versions.

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Smoking Associated With Worsened Symptoms, Quality of Life in Patients With Psychosis

A negative association between number of cigarettes per day and quality of life was observed in patients with psychosis.

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Insomnia Increases Emotional Dysregulation, Impulsivity, and Suicidality in Bipolar Disorder

Sleep has important functions for the regulation of mood and emotion, and treatment of sleep disturbances in bipolar disorder may improve patient outcomes.

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