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NDA Submitted for Novel Insomnia Treatment Lemborexant

The NDA includes data from two Phase 3 clinical trials (SUNRISE 1 and SUNRISE 2) which included approximately 2000 patients.

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Childhood Physical Violence Associated With Decreased Total Cholesterol

Investigators examine the link between decreased total cholesterol and childhood physical violence.

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How the Government Shutdown Affects FDA Activities

The consequence of the shutdown means the budget appropriated by Congress for the Agency is on hold, resulting in ~7000 of it’s 17,000 employees being furloughed.

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The Robot Will See You Now: The Increasing Role of Robotics in Psychiatric Care

Dr Pransky shares some examples of robots that have shown impressive psychiatric applications, as well as her thoughts on giving robots the critical role of delivering healthcare to human beings.

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Extended-Release Naltrexone Improves Psychiatric Disorders During Addiction Therapy

Changes in anxiety, depression, or insomnia symptoms were examined in patients with opioid use disorder taking extended-release naltrexone or buprenorphine-naloxone.

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Infections, Antibiotics Associated With Subsequent Increased Risk for Mental Disorders in Youth

The risk for mental disorders increased after severe infections requiring hospitalizations in children.

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Nonmedical Prescription Opioid Use Motivated by Pain Relief in Adolescence Predicts Later SUD

A set of characteristics of nonmedical use of prescription opioids in adolescents may help identify youth at high risk for substance use disorder, including opioid misuse, in early midlife.

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Pregnancy Reduces the Risk for Alcohol Use Disorder Among Women and Their Partners

Despite the reduction in the ability to exercise free will associated with substance use disorders and the severity of these disorders, pregnancy appears to have protective effects.

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Schizophrenia Risk Alleles, Peer Victimization Associated With Emotional Problems in Youth

Peer victimization may be an important modifiable factor in improving the developmental course among children.

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Sudden Symptomatic Improvement Predicts Response to Antidepressant Therapy

Recent evidence suggests that early sudden improvements have lasting effects and occur in most patients receiving antidepressants.

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Subthreshold Pediatric Bipolar Disorder Is a Significant Psychiatric Burden

Researchers evaluated the relationship between pediatric subthreshold bipolar disorder and significant psychiatric impairments and increased rates of suicidality.

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Aspirin, N-Acetylcysteine Effective Adjunctive Treatments in Bipolar Depression

Investigators examine the therapeutic effects of NSAIDs and NAC in patients with bipolar disorder.

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Dental Procedure-Related Opioid Exposure and Later Risk for Opioid Abuse

A substantial proportion of adolescent and young adults receiving opioids for dental procedures may be at higher risk for later opioid use and abuse.

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Higher Neuroticism Linked to Anxiety, Anhedonia in Depression

Researchers sought to determine whether neuroticism significantly contributes to higher anxiety and anhedonia and further studied whether cognitive control leads to lower anxiety.

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Interview-Only Version of Yale-Brown Obsessive-Compulsive Scale Effective for OCD Monitoring in Youth

Study data found that a single 60-minute interview session may be sufficient for capturing obsessive-compulsive symptoms in youth.

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Blood-Based Medication Monitoring May Effectively ID Patient Medication Use

Comprehensive medication monitoring “has merit” in identifying patient compliance.

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Characteristics of Unipolar Mania, Distinct from Bipolar Disorder, Described

Investigators sought to compare differences in clinical characteristics between patients with mania and those with bipolar disorder I.

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