Genetic risk from rare copy number variants and common single-nucleotide polymorphisms may contribute to liability to schizophrenia.

RCADS is often used to measure anxiety and depression and researchers assessed its structural validity for adults, given the life span nature of anxiety.

Investigators examined the efficacy of sertraline and interpersonal psychotherapy vs pill placebo over 12 weeks in woman with postpartum depression.

Lumateperone and follow-on compounds are also being evaluated for bipolar depression, behavioral disturbance associated with dementia, sleep disturbances associated with neuropsychiatric disorders, and other neuropsychiatric conditions including major depressive disorder and autism.

The use of a polygenic risk score for schizophrenia can effectively predict an antipsychotic treatment response after a first episode of psychosis.

Healthcare interventions should assess the multiple layers of a person’s life, rather than simply classifying marginalized groups as vulnerable.

Ketamine, originally approved by the FDA in 1970 as an anesthetic, is increasingly being recognized as an option in treatment-resistant depression.

Psychosis, or a psychotic episode, is characterized by a distorted perception of reality that is often exacerbated by hallucinations or delusions.

Teen patients with epilepsy experience high levels of depressive symptoms, with 13% requiring behavioral health interventions.

The use of ezogabine, a KCNQ channel opener, may improve depression and anhedonic symptoms in patients with major depressive disorder.

Psychotic experiences may be a clinical marker of risk for future suicidal behaviors.

Future studies need to determine whether improvement in cognition with abstinence is associated with improvement in academic and other functional outcomes.

Mindfulness meditation training may reduce negative affect variability in middle-age and older adults.

A recent review found that existing psychosocial interventions using cognitive-behavioral and mindfulness-based approaches had a small but significant effect on quality of life and anxiety outcomes in patients with psoriasis.

Investigators conducted a comprehensive literature review to determine whether CBT is the most effective form of psychotherapy for children with anxiety disorders.

The role of noninvasive brain stimulation of the prefrontal cortex on amygdala threat reactivity in individuals with trait anxiety was examined.